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    1. Bridge Horizon
    2. NGS Core Facilities
    3. Data governance

    A field guide for core-facility IT

    Genomics data governance: from intake to delivery

    A practical checklist for keeping sequencing data, analysis history and client access accountable across projects. Start with your institution's rules, then evaluate the tools that need to support them.

    Read the checklist

    Start with the obligation

    Compliance is a workflow, not a badge

    A core may handle research data with different consent terms, data-use limitations and client agreements in the same week. Decide what applies to each project before selecting storage or sharing defaults. NIH's Genomic Data Sharing Policy applies to certain NIH-funded large-scale genomic studies; its expectations include a sharing plan, appropriate repositories and responsible handling of controlled-access data. NIH policy overview

    If protected health information is involved, have your privacy team determine whether HIPAA applies and what research use or disclosure is permitted. Research data are not automatically outside HIPAA, and removing names alone is not a complete de-identification assessment. HHS research guidance

    The decision trail

    Intake

    Consent and use

    Analysis

    Inputs and versions

    Delivery

    Named access

    Every transfer of responsibility should have an owner and a record.

    Five review points

    Questions to settle before the next sequencing handoff

    01

    Classify the data before intake

    Record the project owner, assay, human or non-human origin, consent and permitted uses. Keep the approval or restriction with the project record, not just in an email thread. A sample ID alone does not establish that data are safe to share publicly.

    Ask: Who approved this use, and where is that decision recorded?

    02

    Map access to the research agreement

    List the core staff, investigators and external collaborators who need each dataset or report. Decide separately who can view, download or manage it. Review access when people change roles or a project ends.

    Ask: Can an investigator see another group's files through a shared folder?

    03

    Keep analysis provenance attached

    For each handoff, preserve the input identifiers, pipeline version, parameters, reference and resulting files. This makes it easier to investigate a surprising result and explain which analysis produced a deliverable.

    Ask: Could someone reproduce the report without reconstructing the workflow from memory?

    04

    Treat delivery as an access decision

    Confirm recipient identity, the exact files and folders, download rights and whether a time limit is required. Do not mistake a link for authorization, or assume that a link expires by default.

    Ask: Who can open the link after it has been forwarded?

    05

    Document retention and disposition

    Agree on retention periods, archival location, deletion responsibilities and incident escalation with your institution and client. Those terms depend on the data and agreement; a product setting is not a substitute for policy.

    Ask: What happens to raw reads and reports when the engagement closes?

    Putting the checklist to work

    What to inspect in Bridge Horizon

    Bridge Horizon can help keep analyses and handoffs together. Your team still owns its consent review, policy decisions and assessment of whether a particular deployment meets contractual or regulatory requirements.

    Project-scoped sharing

    Show a named recipient only the relevant project, dataset, report, folder or files. The person granting access may choose an expiry; links do not expire by default.

    Run context

    Review input files, pipeline runs and their resulting reports in the same workspace, rather than handing over an unexplained folder of outputs.

    Questions for your IT review

    Ask us to walk through access boundaries, audit evidence, retention and deployment options against your institution's requirements. Do not assume a compliance certification from these features alone.

    Explore Bridge Horizon for NGS cores

    Policy references

    These primary sources explain the policy context. Your institution's privacy, security and research offices should determine what applies to a specific project.

    • NIH: Genomic Data Sharing Policy overview
    • NIH: Developing Genomic Data Sharing Plans
    • NIH: Responsible use of genomic data
    • HHS: HIPAA research guidance

    Review your own workflow

    Bring your data-governance questions to a demo

    We can walk through a core-facility handoff, from analysis history to named client access, and discuss what your IT team needs to validate.

    One place to run pipelines, review results, and share data across your whole genomics team.

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